ncRNA name | hsa-miR-508-3p |
ncRNA Category | miRNA |
Disease name | uveal melanoma (UM) |
Species | Homo sapiens |
Tissues/Cell_line | UM cell line OCM‐1A; human embryonic kidney cell line HEK293T |
Methods | qPCR, Western blot, transfection, proliferation assay, transwell assay, wound healing assay, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | The findings of the presents study demonstrated that the miRNAs of the miR-506-514 cluster, hsa-miR-592 and hsa-miR-199a-5p were the most deregulated miRNAs in patients with high-grade disease compared to those with low-grade disease and were strictly related to the overall survival (OS) of the patients. |
PubMed ID | 30816460 |
Year | 2019 |
Title | Prognostic significance of deregulated microRNAs in uveal melanomas. |
Drug-related ncRNA | NO |
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